The game kicks off at 12.30pm local time, 11.30am in the UK, between two sides who are desperate for points.
The Giallorossi had to leave behind Daniele De Rossi, Jeremy Menez, Adriano and Simone Perrotta. Julio Sergio made the trip a month after he badly sprained his ankle, but is not even on the bench.
Perrotta was suffering from a flu virus and there were reports this morning that it had spread to Totti, but that does not appear to be the case.
